2024 Masters Projects

ProjectSupervisor
Bio-inspired and biomimetic material designs for 3D print applications

Many biological tissues and materials exhibit elaborate and beautiful structures and designs at microscopic scales that are visible in X-ray or electron microscopy or tomography studies. Many of these have functionality that has been refined through millions of years of evolution, leading to efficient and effective solutions. Biomimetics and biomimicry attempt to harness some of biology's features for material design solutions, including in 3D printing and other free-form fabrication methods. This project proposes to explore biological material structure in butterflies, beetles, crustaceans, corals, plants or other organisms through microscopy or tomography studies and to replicate the structural forms in 3D printing for material analysis. There is flexibility within this project as to the specific organism studied and as to choice of focus on microscopy, material design or biological function. .

Gerd E Schroder-Turk
ProjectSupervisor
Mentors and mentoring in initial teacher education: Generating systems-based policy and practice to enhance engagement and outcomes.

Professional Experience placements are a core, mandatory component of Australian initial teacher education (ITE) (Le Cornu, 2015). These Work Integrated Learning (WIL) components provide pre-service teachers (PSTs) with authentic teaching experiences under experienced mentor teachers. The participation and engagement of mentor teachers in ITE is voluntary throughout Australia and relies heavily on their good will (Ledger et al., 2020), yet this involvement is fundamental to the outcomes associated with ITE (Le Cornu, 2016). This emphasises the need for coherent systems that operate between universities and WIL settings to cultivate quality placement experiences (Grossman, 2010). Various legislative and funding arrangements create ambiguity and complexity in relation to partnership (Ledger & Vidovich, 2018) and inhibit system-wide approaches to effectively and efficiently create aligned systems of practice and collaboration (Ure et al., 2017). These enduring challenges are currently being exacerbated by a rapidly changing workforce, in response to disruption caused by the COVID-19 pandemic and resultant national teacher workforce shortage. Moreover, improving the quality of practical experience in teaching is a priority reform area within the Strong Beginnings: Report of the Teacher Education Expert Panel (Department of Education, 2023). This research project examines data produced within Australian universities in relation to the workforce of mentor teachers participating in WIL from 2017 to 2022 to develop enhanced understanding of emerging mentor teachers in order to develop targeted workforce strategies. 

Chad Morrison
ITE-EXTEND systematic literature review

Australian Initial Teacher Education (ITE) has a long history of significant and sustained monitoring, evaluation and critique. This has resulted in increased external accountability through national program accreditation and evaluation, including accountability measures to ensure program quality and graduates' capabilities. Murdoch University’s ITE courses are rigorously designed, accredited, delivered and evaluated within this accountability framework and its courses are contemporary and responsive to the expectations and requirements of industry, community and policy. The current context of teacher workforce shortages, increasing demands of teaching, and external pressures on teaching candidates has resulted in declining ITE enrolments and rapidly evolving pathways into teaching. This provides an opportunity for innovation in ITE course design. This project will align an aRMT candidate with a research team as they pilot an innovative approach to ITE. The candidate will undertake a systematic literature review of ITE, exploring the interconnected themes of school- and university-based ITE preparation, internship, pre-service and early career teacher attraction, retention and traction and the policy environment in which this work is situated. Working under a team of experienced educational researchers, this systematic review will underpin research activity and engagement throughout the pilot and potentially offer the successful candidate opportunities to engage in further research within a team of educational researchers within the School of Education. 

Chad Morrison
Mapping the footprint of elite private schools: A comparative spatial analysis 

Elite private schools are defined as schools that charge high fees and enjoy high status and reputation. Elite private schooling may cause macro educational inequalities and inefficiencies when its footprint is too large and its linkages with high-status occupations and social status is too tightly coupled. Given its very large private school sector, the number and enrolment share of elite private schools is likely to be greater in Australia than in other English-speaking countries. The aim of this study is to test this hypothesis by mapping the footprint of elite private schooling in Australia compared to its “Five Eyes” partners, namely Canada, New Zealand, the UK and the US. Using publicly available data, geographic information system software and a comparative case study design, the aim of this study is to examine the prevalence, geolocation and enrolment share of elite private schools in the major cities of the five countries. 

Laura Perry

Cross-national analyses of educational equity and effectiveness
This study will use an innovative analytical approach, Qualitative Comparative Analysis (QCA), to examine educational equity and effectiveness in five or more countries that participate in the Organisation for Economic Cooperation and Development’s Programme for International Student Assessment. Specific countries and topics can be chosen by the candidate in consultation with the supervisors. The list of potential topics is wide ranging; some examples are the causes of rural educational disadvantage; cross-national differences in student-wellbeing, sense of belonging or life satisfaction; and policies that reduce achievement gaps and educational inequalities.

Laura Perry

Vocational education and training for the Australian government’s manufacturing agenda
The Australian government has prioritised the development of high valued-added manufacturing in the food and beverage, medical products, renewable energy, mineral processing, defence, and aeronautics sectors. A major challenge in developing Australia’s manufacturing capacity in these sectors is a shortage of skilled labour. Finding ways to develop Australia’s labour force is therefore essential for meeting its manufacturing priorities. One strategy for developing labour skills is through vocational secondary education and training. The aim of this study is to identify models from other countries that could provide insights for the Australian context. The findings of the study will lead to specific recommendations about how vocational secondary education and training can be leveraged to meet Australia’s skilled labour needs in high value-added manufacturing.

Laura Perry
Specialist programs in secondary schools: benefits and challenges 
Secondary schools in Australia are increasingly adopting specialist programs to cater to student needs, increase student engagement, and compete with other schools for student enrolments. This aRMT project comprises a systematic review of the benefits, opportunities, challenges, barriers and limitations of specialist programs in secondary schools. 
Laura Perry
Student well-being in the Programme for International Student Assessment 
Student well-being is an important facet of education that has been receiving increased attention of the last several years. The Programme for International Student Assessment (PISA), the largest international student assessment in the world, collects data from 15-year students about cognitive, social, physical and psychological wellbeing. This aRMT project comprises a systematic review about wellbeing as measured on PISA and its relation with academic achievement and other educational outcomes. 
Laura Perry
ProjectSupervisor

Is it better to have large workers or more of them?
Trade-offs of group size and worker size in ants Social animals must choose where to invest their limited resources to maximise group competitiveness. For ants, there is a proposed trade-off between investing in the inpidual size of workers and the size of the colony. This trade-off affects how and where ants can live. For example, previous work has suggested that invasive ants should invest less in inpidual size and more in producing large colonies. We are seeking interested students to help us investigate this trade-off, which is fundamental to the fitness and strategy of ant colonies, and the environmental and social factors that control it. Approaches could include conducting a comprehensive meta-analysis and/or review to determine whether such a trade-off is consistent across ant species, and categorising ants along the trade-off curve according to such features as invasiveness, pest potential, habitat, diet, and foraging strategy.

If interested, please contact Sam at Samuel.lymbery@murdoch.edu.au

Cognition and Warfare Humans aren’t the only animals that go to war.
The mechanisms of non-human warfare, however, remains an understudied and exciting area of research. This project will use ants, the ideal model system for such studies, this system to examine the link between success in group battles and a crucial element of animal behaviour: cognitive ability.

There will be opportunity for students to work flexibly with us to develop their own projects within this over-arching goal. Broadly, we envision assaying the cognitive abilities of inpidual ants, constructing experimental armies from relatively “smart” or “stupid” inpiduals, and staging laboratory battles between these armies. This work will provide valuable data on ant cognition, and generate insights into the relative success of ant species. Since ants are one of the world’s most important groups of animal pests, such information is always of practical importance as well as fundamentally advancing the study of non-human warfare.

Redesigning sea containers to mitigate incursion risk
Exotic pests, diseases and weeds can hitch a ride to Australia inside shipping containers. Sea containers are demonstrated vectors to many economically important quarantinable insects, including timber pests, agricultural pests, environmental pests, and nuisance pests. The Harry Butler Institute is working with the Department of Agriculture Forestry and Fisheries to identify hotspots within sea container for pest refuge and to redesign niches to reduce the risk of incursion into Australia. We are looking for students who are passionate about protecting Australia’s biopersity and agriculture industry to join this project. Students can work with us to arrive at targeted projects, and examples could include:

  • Matching microclimate and habitat variables within shipping containers to preferences of pest species
  • Investigating the role of diapause in resistance to control measures and how this may change management approaches
  • Optimising lure placement for effectively detecting pest presence/absence"
Samuel Lymbery
ProjectSupervisor
Physical activity is an essential component of managing and improving health in multiple sclerosis (MS). MS is the most common non-traumatic neurological condition affecting young adults in Australia. Exercise for people living with Multiple Sclerosis

Available projects will see you engaging with people with MS, for example through 1. a project which monitors the delivery and effects of online exercise programs, 2. a focus group project to understand their opinions on monitoring physical activity. You will work with established researchers and be joining other students working together to answer similar research questions. 

If you are interested in a career in clinical healthcare, underpinned by evidence based practice & promotion of positive health behaviours these projects are for you. Over the course you will improve your research skills in literature reviews, engaging with consumers, data gathering, data analysis (quantitative & qualitative) and presentation of research evidence to both the scientific and consumer community. 

Yvonne Learmonth
ProjectSupervisor
The Fortescue Marsh is a recognised Important Bird Area (IBA), supporting 187 bird species and up to 270,000 waterbirds when inundated. As part of Western Australia’s commitment to be carbon neutral by 2050, many Pilbara mining companies have announced their intention to move to wind and solar energy for their operations. While an important step towards reducing climate change, this shift to renewable energy could have biodiversity impacts that need to be considered as part of green energy planning and commissioning. Understanding which bird and bat species are likely to be using proposed sites is an important first step towards identifying potential risk. This project will compile a list of all bird and bat species reported in published and available grey literature for a 10,000 km2 area centred around the Fortescue Marsh, and compile a traits database for these species to calculate (a) wing loading (the weight of the bird / surface area of the wing), and (b) aspect ratio (wing length /wing width). Missing data will be compiled through measurement of museum specimens. These data will then inform species-specific flight risk windows and provide input values to Collision Risk Models (aerodynamic ability, flight speed, altitude and directionality), which can then inform conservation management decisions.

Feral cats can be difficult to monitor and control due to neophobia and trap avoidance behaviour, resulting in low detection rates and variable success of control measures. We will test a novel, long-life (up to 1 year) lure system to increase camera trap success and reduce neophobic behaviour of cats. Using this lure, we will develop a monitoring system to record feral cat activity, comparing between three camera types and identifying individual cats from distinctive markings.

 

Trish Fleming

Are all Phytophthora species invasive? Phytophthora dieback cause by the invasive pathogen Phytophthora cinnamomi has devastated impacted natural ecosystems in Western Australia.  In mapping its presence, 70 other Phytophthora species have been recovered some of which appear to be native, some introduced.  The bridgehead effect suggest that new species arrive, becomes established in urban environments and then spread into natural ecosystems.  However, traits of the species and environmental filtering, may influence invasiveness.  This project would use the extensive database  and targeted sampling from Western Australia to interrogate these principals.

Diversity of pathogens in stressed forest ecosystems
The  decline of forests worldwide is driven by multiple stressors including disease, fire and drought. Unfortunately, the interactions of multiple stressors may increase a forest’s susceptibility to future stressors. For example, a forest that has experienced drought and fire may have reduced health and vigour and thus be more prone to pathogen incursions. This project will determine how prone these stressed forests are to future pathogen incursions. We will quantify the diversity of pathogens and compare to the diversity of pathogens in healthy forest.

Pathogen accumulation in healthy vs disturbed forests
Habitat fragmentation has resulted in forest fragments spread throughout other land uses (i.e. farming and horticulture). The edges of these fragments are more prone to human and animal traffic and increased access for invasive species including pathogens. This project will determine whether plant species along these disturbed edges accumulate more pathogens than plant species in the forest's interior. Roots from multiple plant species in these two distinct areas will be collected and root fragments plated on selective media for culturing of potential fungal and oomycete pathogens.

Susceptibility of invasive and native plant species to plant pathogens
Invasive plant species can alter plant communities and pose a risk to native plants through pathogen accumulation. Invasive plant species may be less susceptible to some plant pathogens, acting as reservoirs that can increase transmission to native plant species. This project will determine the susceptibility of invasive and native plants to various plant pathogens through leaf/branch assays. The student will inoculate the various host material and measure lesion growth over time. This project will enhance knowledge of the host range of important plant pathogens and highlight possible hosts that may act as reservoirs or be less susceptible.

 

Sarah Sapsford and Treena Burgess

How to court a jumping spider using chemicalsDid you know that the largest living land animal, the Asian elephant (Elephas maximus) shares the same sex pheromone as 140 species of moth? Although it is unlikely that elephants and moths will choose the incorrect mate, this sharing of sex pheromones demonstrates the ubiquity of pheromones across the animal kingdom. This project will investigate the sex pheromones used by the jumping spider Menemerus nigli. Jumping spiders are known for complex courtship displays with both visual, vibratory, and chemical components. The jumping spider Menemerus nigli is considered non-indigenous to Australia and results from this study will be used to determine the feasibility of isolating chemicals for use as a lure in traps. 

Aliens among us - biosecurity matters 
Rats on Gough island that attack adult albatross and dive into water to prey on crabs. Possums in New Zealand that forego their plant-based diet for native bird eggs. Fire ants in Australia who are known to wipe out entire native ecosystems. These invasive species, and many more, are causing significant environmental and economic harm and their numbers are accelerating as the world becomes ever increasingly connected. Invasive alien species are considered one of the five direct drivers causing a global decline in nature and without significant transformation to support a global sustainable pathway, it’s only going to get worse. We are using a multidisciplinary approach (evolutionary, ecology, chemical, computer science, social science) to develop innovative solutions that will help staunch the flow of invasive species from moving around the globe. If you are interested in this area of research, please contact me to discuss project options that will suit your own interests and strengths. 

 

Melissa Thomas
See this video for summary of the project https://www.youtube.com/watch?v=w42SXNeUKzw
This fully funded project will determine the response of an aquatic ecosystem to the first re-snagging program of a channalised river system in south-western Australia. The student will collect data from the third post-restoration monitoring in autumn 2024 and in doing so skill themselves in standardised sampling (that are also used by State Government scientists) of fish, crayfish, mussels, turtles and macroinvertebrates. They will them combine that information and analyse it with our existing dataset to quantify how the aquatic ecosystem has changed in response to re-snagging of the Harvey River. 
Skills attained will include species ID, univariate and multivariate analyses, along with enhancing their knowledge on aquatic biodiversity.  This high-project project will suit a student who has an interest and passion for the conservation of native fauna and is pursuing a career in the research or management of aquatic ecosystems.
Stephen Beatty
ProjectSupervisor
Defining blood lipoprotein marker parameters in childrenCurrently 112 Plasma lipoprotein concentrations can be measured in a 4 min assay using nuclear magnetic resonance spectroscopy. This assay forms part of the InVitro Diagnostics Research (IVDr) platform from Bruker (Bruker LTD) and contains biomarkers of CVD risk. We have validated the adult lipoprotein model by characterising the lipoprotein perturbations in the Busselton cohort: an adult population where samples from 1976 individuals collected at two timepoints were analysed to get lipoprotein concentrations of healthy individuals in comparison to those with different medical conditions (10.1016/j.jacl.2023.06.004). To date little is known about the expected lipoprotein ranges in children and the perturbations that arise due to disease. This project will analyse blood collected from children at ages 1, 3 and 5 to determine the expected ranges in children that are deemed healthy and how these become altered in different disease states (eg. Asthma, eczema and diabetes).  
Integrative plasma metabolic and lipidomic modelling of acute phase burn injury in children
The Australian National Phenome Centre laboratory routinely measures thousands of metabolites using a combination of Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). A recent study within the centre (DOI:10.3389/fpubh.2023.1105163) showed that children 3 years post burn injury demonstrated metabolic signatures of hyperglycaemia, hypermetabolism and inflammation and an increased risk of cardiovascular disease in the long-term independent of burn severity. This project will analyse the blood plasma of children using NMR and MS to understand the metabolic and lipidomic perturbations that arise in the acute phase of burn injury. In addition, follow up samples of the same patients will be analysed and using the associated clinical metadata of the samples statistical modelling will be completed to determine if a specific plasma metabolomic and lipidomic signature in the acute phase leads to better clinical outcomes.
Supervisors - Dr Sam Lodge and Prof Fiona Wood
 
Exploring longitudinal metabolic markers through day-to-day, weekly, and monthly variation in healthy individuals
The ANPC laboratory can routinely measure thousands of metabolites using a combination of Nuclear Magnetic Resonance and Mass Spectrometry. Metabolites such as lipids and lipoproteins indicate an individual's health. Comparing biomarkers from healthy individuals and others with medical conditions (such as diabetes, COVID-19 etc.) is a key step in understanding metabolic disturbances and diseases aetiology. However, little is known regarding the 'normal' fluctuation of metabolism within a day, between days and even across months in each individual, resulting in unwanted noise in the statistical models. Recent advances in the lab allow small blood volume self-collection, allowing repeated sample collection with reduce patient burden. This project's initial work is to help understand variations due to lifestyle (diet, exercise, circadian rhythm, etc.) on metabolic signature of individuals. It is hoped that the study's results will allow for future personalised health and monitoring applications taking science from the 'bench' to the ‘community’.
Exploring lifestyle choices and how they influence metabolic markers in healthy individualsThe ANPC laboratory can routinely measure thousands of metabolites using a combination of Nuclear Magnetic Resonance and Mass Spectrometry. Metabolites such as lipids and lipoproteins indicate an individual's health. Comparing biomarkers from healthy individuals and others with medical conditions (such as diabetes, COVID-19 etc.) is a key step in understanding metabolic disturbances and diseases aetiology. However, little is known regarding the 'normal' fluctuation of metabolism due to lifestyle choices adding unwanted noise in statistical models. Recent advances in the lab allow small blood volume self-collection, allowing repeated sample collection with reduce patient burden. This project's initial work is to help understand variations due to lifestyle (diet, exercise, circadian rhythm, etc.) on metabolic signature of individuals. It is hoped that the study's results will allow for future personalised health and monitoring applications taking science from the 'bench' to the ‘community’.

Characterising our innate immune response to viral infection mediated by the RSAD2 pathway
Due to their adverse impact on healthcare systems, COVID-19, and the causative agent SARS-CoV-2, have been the subject of intense clinical and biochemical study over the last three years. In addition to understanding the clinical impact of SARS-CoV-2 infection, it is important to broaden our understanding of the length of the infectious period and possible shortcomings of direct viral testing.
Work in our laboratories has discovered several candidate biomarkers in human urine, derived via modified nucleotide metabolism and linked to the RSAD2 gene, with potential clinical application in acute viral infection diagnosis. In this project we hope to further characterise the biomarker response, as well as provide an in-depth correlation to clinical parameters already acquired for cohorts under investigation. The project is not restrained and can be tailored to the individual interests of students applying for the project, for instance: analytical chemistry, or bioinformatics.

Supervisors – Samantha Lodge, Samuele Sala, Julien Wist.

Unravelling the Complex Picture of Microbiome-Host Metabolic InteractionsThe human microbiome is a collection of all the microbes, such as bacteria, fungi, viruses, as well as their genetic information, that reside on our bodies, and inside of us. Recent work has uncovered just how large a contribution our individual microbiomes make to our health, along various signalling-axes including defence against pathogens, development of innate and adaptive immunity, energy homeostasis, and the digestion of food and nutrients.
The following project would seek to unravel some of the complex interactions between humans and the microbiome, using a variety of state-of-the-art metabolomic analytical techniques, such as Nuclear Magnetic Resonance and Mass Spectrometry. Data will be analysed using dimensionality reduction techniques, allowing for the detection of key molecules involved in some of the numerous “small molecule” metabolic Host-Microbe signalling axes. 

Supervisors – Sam Lodge, Samuele Sala, Elaine Holmes, Julien Wist

 

Application of Machine Learning to Small Molecule Structure Elucidation
Advances in computational technology, and access to computational resources have brought Density Functional Theory (DFT) prediction of Nuclear Magnetic Resonance (NMR) spectra well within the experimental chemist’s toolbox, as evidenced by the extensive adoption of quantum mechanical techniques within structural elucidation literature over the past decade. Recently, application of machine learning and statistical methodology, both at the level of chemical shift prediction, and decision making from ensembles of isomers, have represented an improvement of several orders of magnitude over previous quantum mechanical methods in terms of raw computational time, and accuracy. 
The following project would seek to integrate various existing and open-source chemical shift prediction algorithms (e.g., CASCADE, NMRshiftdb-NN, etc.), with alternative open-source decision making algorithms (e.g., CD3, DP4+, etc.). Benchmarking would be achieved on an ensemble of test molecules. The project seeks a student with an interest in organic chemistry and informatics.

 
Unlocking Cardiovascular Disease Risk: Heart-Healthy Diets and Plasma LipidsCardiovascular disease (CVD) is the leading cause of death globally, accounting for 17.8 million deaths per year. There is widespread consensus that diet plays a key role in reducing CVD risk. Cutting-edge lipidomic profiling, capable of measuring hundreds of lipids in plasma, is particularly relevant to understanding the mechanisms of CVD, as lipids have been shown to play a crucial role in its pathophysiology. However, the impact of different diets on lipid levels remains unclear. This project aims to address this gap.  The student will utilise plasma samples from a randomised three-period crossover feeding study that compares the effects of plasma lipids from three different heart-healthy diets: a carbohydrate-rich diet patterned after the DASH diet (CARB), a diet rich in protein (PROTEIN), and another rich in unsaturated (UNSAT) fats, predominantly monounsaturated fats.

Defining Healthy lipoprotein ranges in the Busselton cohort and comparison with a large Spanish Cohort. Through improvements in modern medicine, our life expectancy has increased globally, as well as the number of those suffering from metabolic syndrome such as diabetes, and cardiovascular disease. With the rise of an aging population, it is difficult to define “Healthy” due to existing conditions. We have collected and validated plasma lipoprotein from the Busselton cohort (1976 individuals at two timepoints) and serum lipoprotein from a large Spanish cohort (n = 14,000) at one timepoint using nuclear magnetic resonance (NMR) spectroscopy InVitro Diagnostics Research (IVDr) platform from Bruker (Bruker LTD). This project aims to define the lipoprotein ranges of “Healthy” from two geographically separated cohorts and compare them to find the similarities and differences between the two.
 

Samantha Lodge
ProjectSupervisor
Proposed Project: Predicting Employee Cybersecurity Violations: Comparison of Theoretical Model and Machine Learning Model

The proposed research aims to examine factors behind employees violating cybersecurity policies. While existing cybersecurity behavioral studies focus primarily on organizational, environmental, and behavioral factors, a growing body of literature suggests individual differences such as personality traits as a strong predictor of cybersecurity violations. For instance, extroverted employees, due to their inherent risk-taking nature, might often bypass security guidelines. Given that 90% of cyberattacks originate from human actions, this project seeks to identify factors that contribute to cybersecurity violations using established human behavioral theories and incorporating individual factors such as personality traits. Based on the identified factors, the ultimate goal of the proposed project is to develop and test a theoretical using statistical techniques such as structural equation modeling, and a propose a machine learning model. A comparison between the two models and how well they predict cybersecurity violations key and the novelty of this research.

Florence Mwagwabi
Project Supervisor
Modelling genotype x environment interactions and their translational effects on plant phenotypes

With the fast development of Next Generation Sequencing technologies, hundreds of crop accessions have been genetically profiled. The large volume of genomics data will be incorporated into phenotyping data and environment variables measured in large field trials across Australia to develop genotype to phenotype predictive models. Such models predict phenotypic traits as functions of genotypic and environmental inputs as well as their complicated interactions. The project will have access to thousands of high-density genetic markers and variations obtained by other methods, which will boost the reliability of the models that can predict phenotypes using multi-level genomics profiles. The project will also evaluate the prediction of gene sets that can give optimal barley yield and quality given a specific environmental condition. Using machine learning, new models will not only provide a framework for de novo breeding and precision agriculture, but give a new systems biology perspective in the context of crop genetics.

Penghao Wang
Fast and automatic deep learning-based crop phenotyping methods using remote imagery

Improving crop grain yield and other important quality, including heat and drought tolerance, disease resistance, etc, rely on understanding the regulatory interaction between genotype and environment and identifying the genes controlling crop genotypes. This requires mapping the phenotypic performance of large number of genotypes under different environmental conditions. The fast development of Next-Generation Sequencing technology has enabled sequencing thousands of oat germplasms and made available large amounts of genomic resources, including the oat pan-genome. On the contrary, phenotyping remains a labour-intensive process and desperately needs a high-throughput approach. The project aims to develop a fast and automatic phenotyping method using deep learning-based image analysis. The project will develop skills in state-of-the-art deep learning methods and have access to more hundreds of Gigabytes of image data from > 900 oat varieties.

Penghao Wang
Project Supervisor
The Green and Gold of Australian butterflies

Butterflies – and moths, beetles and insects more generally – have evolved many creative ways of producing green coloration, with or without metallic or iridescent shimmer. Some use green pigmentation, but most appear green by developing diverse types of structural coloration or optical effects. These structures are often highly complex and can create polarization, iridescence and spectral effects. Why butterflies have evolved so many different solutions to producing green coloration remains unclear. In this project you will conduct a stocktake of the mechanisms for generating green coloration used by Australian butterflies, based on spectral analysis and electron microscopy or tomography. This knowledge will then be compared across the lepidopteran phylogeny and against important ecological variables to understand better the evolutionary drivers of green coloration strategies in butterflies. Depending on the student’s interests, the project can be extended to assess whether spectral properties of butterfly coloration can be used in automated species recognition based on deep learning approaches of hyperspectral images.

Annie Jessop
ProjectSupervisor
Improving working memory in older adults through the synergistic effect of physical activity and non-invasive brain stimulation on brain connectivity
Working memory (WM) function is essential for day-to-day activities such as driving and conversing with family and friends. Unfortunately, declines in WM are quite common for older adults (Kramer et al., 1999). Physical exercise is known to be effective in reducing the impact of age on cognitive decline (Law et al., 2020). Similarly, there is good evidence to suggest that transcranial alternating current stimulation (tACS) can also ameliorate cognitive decline in older adults (see review, Tan et al., 2018). In this project, we investigate whether combined exercise and NiBS intervention can achieve greater improvement in WM compared to either exercise or NiBS on its own.
NOTE: Students working on this project will gain profound insights into brain functions and will have an opportunity to gain experience in using cutting-edge non-invasive brain stimulation techniques and state-of-art EEG techniques and analyses.

References
Kramer, A. F., Hahn, S., & Gopher, D. (1999). Task coordination and aging: explorations of executive control processes in the task switching paradigm. Acta Psychologica, 101(2–3), 339–378.
Law, C.-K., Lam, F. M. H., Chung, R. C. K., & Pang, M. Y. C. (2020). Physical exercise attenuates cognitive decline and reduces behavioural problems in people with mild cognitive impairment and dementia: a systematic review. Journal of Physiotherapy, 66(1), 9–18.
Tan, J., Iyer, K. K., Tang, A. D., Jamil, A., Martins, R. N., Sohrabi, H. R., Nitsche, M. A., Hinder, M. R., & Fujiyama, H. (2018). Modulating functional connectivity with non-invasive brain stimulation for the investigation and alleviation of age-associated declines in response inhibition: A narrative review. Neuroimage, 185, 490–512.

Hakuei Fujiyama
Neural Mechanisms underlying Tourette Syndrome and Potential Interventions to Reduce associated Symptoms

Tourette Syndrome (TS) is a neurodevelopmental disorder characterised by involuntary, rapid, and stereotyped movements (motor tics) or vocalisations (phonic tics) that are present for at least 1 year. The severity of tics ranges from mild and non-impairing to severe and incapacitating, with 29% of patients exhibiting self-injurious behaviours such as head banging or self-hitting. As such, it is unsurprising that TS can have profound consequences on a person’s social life as well as educational and occupational opportunities. However, the exact mechanisms of TS are highly elusive and the understanding of the mechanisms underlying TS would pave the way for developing future interventions. Here, we investigate the neurophysiological mechanisms underlying TS, focusing on brain connectivity using neurophysiological techniques. 

Hakuei Fujiyama
Psychological trauma and alcohol consumption
Preliminary data collected from a student sample at Murdoch University demonstrates that coping drinking motives fully mediate the causal pathway between symptoms of posttraumatic stress and alcohol involvement. In other words, people who experience traumatic events are motivated to consume alcohol in order to cope with their symptoms of trauma. This is evidence in support of the self-medication hypothesis. Various quantitative and qualitative projects to further explore this relationship or phenomenon involve the following research questions: 
1. Does the experience of a Criterion A traumatic event predict coping drinking motives?
2. What are the experiences of drinking amongst participants who have also experienced a traumatic event? (Qualitative project)
3. Does the symptom threshold for drinking to cope decrease over time?
4. Does a cognitive-behavioural treatment intervention that targets coping drinking motives reduce alcohol involvement and/or trauma symptoms for trauma-exposed individuals at risk of alcohol use disorders?

Charles Young
Exercise for people living with Multiple Sclerosis
Physical activity is an essential component of managing and improving health in multiple sclerosis (MS). MS is the most common non-traumatic neurological condition affecting young adults in Australia. 

Available projects will see you engaging with people with MS, for example through 1. a project which monitors the delivery and effects of online exercise programs, 2. a focus group project to understand their opinions on monitoring physical activity. You will work with established researchers and be joining other students working together to answer similar research questions. 

If you are interested in a career in clinical healthcare, underpinned by evidence based practice & promotion of positive health behaviours these projects are for you. Over the course you will improve your research skills in literature reviews, engaging with consumers, data gathering, data analysis (quantitative & qualitative) and presentation of research evidence to both the scientific and consumer community. 

Hakuei Fujiyama
Project Supervisor
1. Prevalence of Theileriosis in pre-weaned calves in the south-west region of Western Australia
2. Studies on causes of morbidity in small ruminants in Western Australia

1. The project will involve laboratory and data analysis
2. Project will involve data analysis

Joshua Aleri
ProjectSupervisor
Neck muscle anatomy and ecology in marsupials

This project will investigate how the muscles of the neck are arranged and their influence on the morphology of the skull across groups of marsupials (kangaroos, wallabies, koalas, possums) through anatomical dissection, medical imaging and/or geometric morphometrics depending on the area of interest of the student. This work will have applications to biomedical research and the interpretation of fossils.
Associate Professor Natalie Warburton (Medical, Molecular and Forensic Sciences)
Associate Professor Martin Cake (Veterinary Science)

2024 Doctoral Projects

ProjectSupervisor
Interventions to improve biodiversity value of carbon projects

This project is part the Industrial Transformation and Training Centre 'Healing Country', which integrates Indigenous Knowledge with restoration science to provide local livelihood opportunities and to restore country. The successful candidate will work towards research and development of effective, scalable restoration technologies to deliver biodiverse, cost efficient restoration that will contribute to the Indigenous Restoration Economy. Funding will be provided for research.

Associate Professor Rachel Standish and others depending on aspect of biological diversity the candidate is interested to study.

ProjectSupervisor
Bird and bat collision risk modelling

Australia is the world's largest iron ore producer (29% of the global total). Most of this iron ore is developed in Western Australia, making up 99% of overall production, the bulk of which has been mined from deposits in the Hamersley province in the Pilbara of Western Australia. Central to the Pilbara lies the Fortescue Marsh, an extensive (10 x 100 km) ephemeral saltmarsh subject to extensive episodic inundation, once every 10 or more years. The Fortescue Marsh is a recognised Important Bird Area (IBA), supporting 187 bird species and up to 270,000 waterbirds when inundated. As part of Western Australia’s commitment to be carbon neutral by 2050, many Pilbara mining companies have announced their intention to move to wind and solar energy for their operations. While an important step towards reducing climate change, this shift to renewable energy could have biodiversity impacts that need to be considered as part of green energy planning and commissioning. Understanding which bird and bat species are likely to be using proposed sites is an important first step towards identifying potential risk. For example, nocturnally migrating birds (species that are on the wing for multiple days) are more exposed than diurnally migrating birds. Raptors, which fly looking down and have limited binocular overlap and poor visual acuity towards the top of their head (likely an adaption to avoid solar glare) are more vulnerable to turbine strike, with Accipitriformes making up the most common bird family impacted by turbine strike. Also, larger birds are more likely to be recovered after turbine strike, while those with slower flight speed are also more vulnerable to turbine strike. In a global meta-analysis of the traits correlated with wind turbine collision for 9,538 bird and 888 bat species, avian collision rate was affected by migratory strategy, dispersal distance and habitat associations, while bat collision rates were influenced by dispersal distance. This project will compile a list of all bird and bat species reported in published and available grey literature for a 10,000 km2 area centred around the Fortescue Marsh, and compile a traits database for these species to calculate (a) wing loading (the weight of the bird / surface area of the wing), and (b) aspect ratio (wing length /wing width). Missing data will be compiled through measurement of museum specimens. These data will then inform species-specific flight risk windows and provide input values to Collision Risk Models (aerodynamic ability, flight speed, altitude and directionality), which can then inform conservation management decisions.

Trish Fleming, Jill Shephard

ProjectSupervisor
Snap-Cat! monitoring feral cats around quokka habitat

Feral cats can be difficult to monitor and control due to neophobia and trap avoidance behaviour, resulting in low detection rates and variable success of control measures. We will test a novel, long-life (up to 1 year) lure system to increase camera trap success and reduce neophobic behaviour of cats. Using this lure, we will develop a monitoring system to record feral cat activity, comparing between three camera types and identifying individual cats from distinctive markings.

Trish Fleming, Melissa Thomas

ProjectSupervisor
Current and Future changes in key climate drivers affecting Western Australian climate extremes from the Coupled Model Intercomparison Project (CMIP6)

The fungal pathogen crown rust (OCR) causes significant damage in Australian oat production. This project aims to identify new sources of enduring high value resistance to OCR, tools to accelerate the use of these resistances, and locally adapted OCR resistant oat germplasm for use in developing profitable oat varieties. It will lead to responsible stewardship of broadly effective OCR resistance in grazing/milling/hay oats, increasing grower profitability, reducing reliance on fungicides, and underpinning planned growth in our export oat market. The PhD project will focus on identification of the resistance genes and develop diagnostic DNA-based markers for high value resistance (R) genes to speed future discovery. This project is part of an ARC linkage project in collaboration with University of Sydney and DPIRD

Professor Chengdao Li (MU), Dr Manisha Shankar (DPIRD), Professor Rajeev Varshney (MU) and Professor Robert Park (USyd)

ProjectSupervisor
Increasing stable lupin productivity through enhanced disease resistances

There are several known fungal and viral diseases that are a constant threat to lupin production across Australia, particularly in WA where over 85% of the world’s lupin crop is produced. Diseases such as Anthracnose, Phomopsis, Cucumber Mosaic Virus (CMV) and Sclerotinia have caused significant yield losses, severe toxicity to livestock, or impacted grain marketability in the past. Reliance on disease resistance of new lupin cultivars in the farming system has been critical to controlling these diseases and minimising their related impacts. However, ongoing reports of yield loss and livestock toxicity despite the availability of disease resistant varieties suggest that there is still considerable room for improvement in enhancing resistance against these pathogens in lupins. An analysis of existing phenotyping methods and genetic resources available to Australian lupin breeders and pre-breeders for the major lupin diseases has identified a range of gaps that need to be addressed to accelerate the development of varieties with improved resistance. The PhD project will focus on identification of disease resistance genes for Anthracnose, Phomopsis and Cucumber Mosaic Virus (CMV. This is part of the GRDC lupin disease resistance project in collaboration with DPIRD, Curtin University and Australian Grain Technology ltd.

Dr Gaofeng Zhou, Professor Chengdao Li, Adj Prof Darshan Sharma (DPIRD) and Dr Jeff Thomas (DPIRD)

ProjectSupervisor
Genetic solutions to Septoria management in oats in WA

Septoria blotch caused by Parastagonospora avenae is a significant oat disease especially in Western Australia where almost all oat crops have some level of Septoria infection. Average yield losses from Septoria in the high rainfall zone are approximately 15% and result in significant economic loss. The Septoria pathogen population is diverse, making breeding for durable resistance difficult and to date little work has been undertaken to identify and characterise genetic sources of resistance to Septoria blotch. The aims of this research are (i) to investigate variation in virulence of P. avenae isolates across regional sites of WA and (ii) to identify novel sources of resistance and provide breeders with the germplasm and tools to breed varieties with durable resistance to Septoria. The PhD position will be one of the above two project areas depending on the student's interest and background. This is part of large national project funded by the GRDC and Western Australia Oat Industry Partnership.

Professor Chengdao Li, Dr Manisha Shankar(DPIRD), Dr Tianhua He, Dr Yong Han (DPIRD)

ProjectSupervisor
The politics of police reform in Western Australia

This project would examine the history of police reform in WAPOL, looking particularly at the dynamics of how reform is proposed, contested and achieved by different groups (political elites, bureaucracy, police reformers and civil society).

Jacqui Baker
ProjectSupervisor
The political economy of critical minerals in Western Australia

How is the Western Australian government readying the regulatory landscape for this new industry? What players are entering the sector and what constraints/opportunities do they find? What kind of labour is necessary for this sector?

Jacqui Baker
ProjectSupervisor
Policing Protest in Australia

In recent year, state and federal governments appear to have shifted their approach and strategies towards the right to protest. There have been numerous changes to protest laws and the use of repressive strategies by the police have been amplified for certain kinds of protestors and causes. What is driving these changes and with what consequence for the future of contestation in Australia?

Jacqui Baker
ProjectSupervisor
Police Use of Force: Permissions and Obligations

The aim of my research project is to conduct an ethical analysis of the principles of defensive harming by police inside well-ordered liberal democracies like Australia. I intend to answer the following research question: How do the special moral obligations of police affect their permissions and obligations to use force? My project is divided into three parts. Part one will describe the permissions of ordinary citizens to use force in self-defence. Part two will explore the permissions and obligations (if there are any) of ordinary citizens to use force in defence of others. Part three will describe the moral obligations which a person incurs when voluntarily undertaking the role of police officer, and describe if and how such obligations affect the role-occupant’s permissions and obligations to use defensive force.

Dr Anne Schwenkenbecher (Murdoch University), Dr Kathryn Trees (Murdoch University) and Dr Adam Henschke (University of Twente)

ProjectSupervisor
Racism and Allyship in Aboriginal Youth Spaces

We invite you to participate in a research study exploring awareness and practices of allyship toward Aboriginal peoples among adults who work with Aboriginal youth. This study is being conducted by a research team of Aboriginal and non-Aboriginal researchers, across research institutions around Australia, but primarily in Perth (Boorloo). Please see the project site for details. Seeking qualitative or quantitative social science researchers with an interest in racism studies in Australia and allyship. Students from all social science disciplines or psychology are encouraged to apply. Aboriginal and Torres Strait Islander students also strongly encouraged to apply.

Rebecca Bennett and Bep Uink
ProjectSupervisor
Exploring Therapies for those who have none

The focus of our laboratory is studying the consequences of rare genetic mutations on gene expression and exploring molecular therapies. This project will explore the best way to diagnose patients with rare diseases, study the functional consequences of mutations and develop personalised nucleic acid therapies.

Dr May Aung-Htut Dr Craig McIntosh Dr Jessica Cale

ProjectSupervisor
Molecular therapies for rare diseases

Our laboratory is one of the world leaders in the development of therapeutic antisense oligomers with three US Food and Drug Administration-approved drugs developed in our laboratory. This project will design and assess antisense oligomer therapies applicable to rare diseases, including Kleefstra syndrome and DYRK1A syndrome using patient-derived iPSC, neurons.

Dr May Aung-Htut Dr Craig McIntosh Dr Jessica Cale

ProjectSupervisor
Understanding the functional consequences of non-coding regions in human genes

Understanding the consequences of mutations in non-coding regions (5'UTR and 3'UTR) in human genes. The project aims to understand the significance of mutation in non-coding regions and will explore the function of mRNA isoforms with alternatives 5' and 3' untranslated regions. This basic understanding will provide us with a better understanding of the pathogenicity of various diseases.

Dr May Aung-Htut Dr Craig McIntosh Dr Jessica Cale

ProjectSupervisor
Improving the delivery of an emerging class of therapeutic, antisense oligomers

One limitation of antisense therapy is effectively delivering to target tissues/cells. This project will explore ways to improve the delivery of therapeutic antisense oligomers to various organs.

Dr May Aung-Htut Dr Craig McIntosh Dr Jessica Cale

How to apply

If you already have a project identified with a potential supervisor, please follow our application process.